diff --git a/devel/py-grpcio/Makefile b/devel/py-grpcio/Makefile
index 5d821dac9a6a..64c5e6a899f8 100644
--- a/devel/py-grpcio/Makefile
+++ b/devel/py-grpcio/Makefile
@@ -1,5 +1,5 @@
 PORTNAME=	grpcio
-PORTVERSION=	1.72.0
+PORTVERSION=	1.72.1
 PORTREVISION=	0
 CATEGORIES=	devel python
 MASTER_SITES=	PYPI
diff --git a/devel/py-grpcio/distinfo b/devel/py-grpcio/distinfo
index 8225ecfe26ef..5977fdf06250 100644
--- a/devel/py-grpcio/distinfo
+++ b/devel/py-grpcio/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1745712769
-SHA256 (grpcio-1.72.0.tar.gz) = 05aee9be958a580e169e1aa8987387bcd8be6ed7fc5c2a3a048b6a2b911473cd
-SIZE (grpcio-1.72.0.tar.gz) = 12588545
+TIMESTAMP = 1748960251
+SHA256 (grpcio-1.72.1.tar.gz) = 87f62c94a40947cec1a0f91f95f5ba0aa8f799f23a1d42ae5be667b6b27b959c
+SIZE (grpcio-1.72.1.tar.gz) = 12584286